Toxicology

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• The classic triad of opioid overdose — pinpoint pupils, depressed respirations, and decreased mental status.

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• An opioid antagonist that reverses respiratory depression caused by opioids; commonly given 0.4–2 mg intranasal or intramuscular.

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• A poison that crosses the skin or mucous membranes — pesticides and some chemicals.

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• A pattern of stimulant overdose — tachycardia, hypertension, hyperthermia, dilated pupils, agitation — from drugs like cocaine or methamphetamine.

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• A poison taken in by mouth — the most common route of exposure in the United States.

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